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庞晓斌

时间:2017年05月17日    来源:    作者:    阅读:

1.个人信息(Personals):

  男,1973年4月生,博士,博士生导师,河南大学特聘教授。河南大学实验动物中心主任,河南省实验动物学会副理事长,河南省药理学会常务理事,中国实验动物学会无菌动物分会常务委员,国家自然科学基金通讯评议专家。Email:pxb@henu.edu.cn

2.受教育经历 (Educational Experience) :

  2003.09–2006.06,吉林大学,生物化学与分子生物学,博士

  2000.09–2003.07,吉林大学,遗传育种,硕士

  1992.09–1996.07,内蒙古民族大学,农学,学士

3.工作经历(Professional Experience) :

  2015.12-至今,河南大学,药学院,教授

  2009.09-2012.08,中国医学科学院药物研究所,博士后

  2008.11-2015.12,河南大学,药学院,副教授

  2006.06-2008.10,河南大学,药学院,讲师

4. 研究兴趣(Research Interests):

  1) 中药药效物质基础与新药开发;2) 阿尔茨海默病发病机制研究。

5. 承担项目情况(Financial Supports)

  (1)“ApoE4介导转基因小鼠炎症反应的AD发病机制研究”,国家自然科学基金面上项目,31872311,57万元,2019/01-2022/12,主持人。

  (2)”消栓通络有效成分组基于"神经血管单元(NVU)"治疗缺血性中风的机制研究”,国家自然科学基金面上项目,81273652,72.00万元,2013/1-2016/12,主持人。

  (3)“脉络宁注射液调控星形胶质细胞谷氨酸转运体GLT-1参与脑缺血后神经血管单元功能重塑的机制研究”,国家自然科学基金应急管理项目,81541072,10万元,2016/01-2016/12,主持人。

6. 代表性论著(Publications)

  1) 期刊论文(Journal Articles) :

  (1)Li QL, Tian ZX, Wang MH, Kou JJ, Wang CL, Rong XL, Li J, Xie XM*, and Pang XB*. Luteoloside attenuates neuroinflammation in focal cerebral ischemia in rats via regulation of the PPARgamma/Nrf2/NF-kappaB signaling pathway. Int Immunopharmacol, 2019, 66: 309-316.

  (2)Qiu, Weiyi, Zhang Chang, Wang Shuang, Yu Xiaoyan, Wang Qiong, Zeng Dadi, Du Peng, Ma Jinling, Zheng Yiqiong, Pang Bo, Yu Yunzhou*, Feng Long, Pang Xiaobin* and Sun Zhiwei*. "A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan." Journal of Immunology Research. 2019.

  (3)Tian, Zixia, Jia Haiyan, Jin Yuezhen, Wang Minghui, Kou Jiejian, Wang Chunli, Rong Xuli, Xie Xinmei*, Han Guang* and Pang Xiaobin*. "Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress in vivo and in vitro." Food & Nutrition Research. 2019, 63: 1667-1681.

  (4)Chang YX, Fu JX, Yao K, Li B, Xu KX*, and Pang XB*. Novel fluorescent probes for sequential detection of  Cu2+ and citrate anion and application in living cell imaging. Dyes and Pigments, 2019, 161: 331-340.

  (5)Yu YZ, Li QL, Wang HC, Liu S, Pang XB*, Xu Q, Zhou XW*, and Huang PT. Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-TF chimeric vaccine. Clinical Immunology, 2018, 193: 12-23.

  (6)Wang CY, Fu JX, Yao K, Xue K, Xu KX*, and Pang XB*. Acridine-based fluorescence chemosensors for selective sensing of Fe3+ and Ni2+ ions. Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy, 2018, 199(15): 403-411.

  (7)Dai YP, Fu JX, Yao K, Song QQ, Xu KX*, and Pang XB*. A novel turn-on  uorescent probe for Al3+ and Fe3+ in aqueous solution and its imaging in living cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 192: 257-262.

  (8)Chen BY, Zhou G, Li QL, Lu JS, Shi DY, Pang XB*, Zhou XW, Yu YZ*, and Huang PT. Enhanced effects of DNA vaccine against botulinum neurotoxin serotype A by targeting antigen to dendritic cells. Immunology Letters, 2017, 190: 118-124.

  2) 论著(Books):

[1] 庞晓斌(参编),中药材【毒】古今研究概评,中国医药科技出版社。42万字,2018.