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杜钢军

时间:2017年05月17日    来源:    作者:    阅读:

1.杜钢军,河南大学,药学院,特聘教授

2.教育经历(从大学本科开始,按时间倒序排序;请列出攻读研究生学位阶段导师姓名):

  2002/9–2005/6, 沈阳药科大学, 药理学, 博士, 导师:王敏伟

  1994/9–1997/6, 沈阳药科大学, 药理学, 硕士, 导师:张宝凤

  1990/9–1994/6, 河南大学, 药学, 学士

3.科研与学术工作经历(按时间倒序排序;如为在站博士后研究人员或曾进入博士后流动站(或工作站)从事研究,请列出合作导师姓名):

  2010/11-至今,河南大学,药学院,教授

  2006/11-2010/10,河南大学,药学院,副教授

  2000/5-2006/10,河南大学,药学院,讲师

  2006/2-2008/6,中国科学院生物物理研究所,博士后,合作导师:梁伟

4.主持或参加科研项目(课题)及人才计划项目情况(按时间倒序排序):

  国家自然科学基金面上项目,81173094、肺癌低氧微环境关键调控蛋白研究、2012/01-2015/12、58万元、已结题、主持。

  国家自然科学基金一年期面上项目,81373974、以穿心莲为代表的中药有效部位肿瘤靶向聚合物胶束研究、2014/01-2014/12、16万元、已结题、参加。

5.代表性研究成果和学术奖励情况

  一、期刊论文(仅不列此项时可删除该标题)

  请按如下顺序列出:

  第一作者论文(仅不列此项时可删除该标题)

  (1)  Du Gangjun(#) (*),Li Jiahuan  (#),Liu Weijie,Liu Yinghui,Zhao Bei,Li, Hongru,Hou Xidong,Li Hong,Qi Xiaoxiao,Duan Yongjian (*).The combination of TRPM8 and TRPA1 expression causes an invasive phenotype in lung cancer,Tumor Biol,2014,35(2):1251-1261。

  (2) Du Gangjun(#) (*),Zhao Bei(#) ,Zhang Yaping,Sun Ting,Liu Weijie,Li Jiahuan,Liu Yinghui,Wang Yingying,Li Hong,Hou Xidong,Hypothermia Activates Adipose Tissue to Promote Malignant Lung Cancer Progression,Plos One,2013,8(8):1-10。

  (3) Du Gangjun(#) (*),Liu Yinghui (#),Li Jiahuan,Liu Weijie,Wang Yingying,Li Hong,Hypothermic microenvironment plays a key role in tumor immune subversion,International Immunopharmacology,2013,17(8):245-253。

  (4) Du Gangjun(#) (*) (#),Yang Yiming (*),Zhang Yaping,Sun Ting,Liu Weijie,Wang Yingying,Li Jiahuan,Zhang Houyun,Thrombocytosis and immunohistochemical expression of connexin 43 at diagnosis predict survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy,Cancer Chemotherapy and Pharmacology,2013,71(3):893-904。

  (5) Du Gangjun(#) (*) ,Sun Ting(#) ,Zhang Yaping,Lin Haihong,Li Jiahuan,Liu Weijie,Wang Yingying,Zhao Bei,Li Hongru,Liu Yinghui,The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis,European Journal of Pharmacology,2013,715(2-3):395-404。

  通讯作者论文(勿与第一作者论文重复)(仅不列此项时可删除该标题,序号按实际情况编排)

  (1) Cao Ning (#),Ma Xiaofang (#),Guo Zhenzhen,Zheng Yaqiu,Geng Shengnan,Meng Mingjing,Du Zhenhua,Lin Haihong (*),Duan Yongjian,Du Gangjun(*),Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity,Oncotarget.,2016.9.20,7(38):61093~61106

  (2) Geng Shengnan (#),Zheng Yaqiu(#),Meng Mingjing,Guo Zhenzhen,Cao Ning,Ma Xiaofang,Du Zhenhua,Li Jiahuan(*),Duan Yongjian, Du Gangjun(*),Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model,J Agric Food Chem,2016.8.10,64(31):6203~6211

  (3) Li Ganggang(#),Guo Zhenzhen(#),Ma Xiaofang,Cao Ning,Geng Shengnan,Zheng Yaqiu,Meng Mingjing,Lin Haihong,Han Guang(*), Du Gangjun(*),T he M2 macrophages induce autophagic vascular disorder andpromote mouse sensitivity to urethane-related lung carcinogenesis,Developmental and Comparative Immunology,2016.1.15,59(1):89~98

  (4) Xiaofang Ma (#),Jiaxiu Deng(#),Ning Cao,Zhenzhen Guo,Yaqiu Zheng,Shengnan Geng,Mingjing Meng,Haihong Lin,Yongjian Duan(*),Gangjun Du(*),Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro,Toxicology Letters,2016.1.10,240(1):130~139

  (5) Hong Li(#),Ganggang Li(#),Linxin Liu,Zhenzhen Guo,Xiaofang Ma,Ning Cao,Haihong Lin(*),Guang Han,Yongjian Duan,Gangjun Du(*),Tumor interstitial fluid promotes malignant phenotypes of lung cancer independently of angiogenesis,Cancer Prev Res,2015.9.3,8(11):1120~1129

  (6) Liu Linxin(#),Li Hong(#),Guo Zhenzhen,Ma Xiaofang,Cao Ning,Zheng Yaqiu,Geng Shengnan,Duan Yongjian,Han Guang (*),Du Gangjun(*),The combination of three natural compounds effectively prevented lung carcinogenesis by optimal wound healing,PLos One,2015.11.23,10(11):e0143438~21

  授权发明专利(仅不列此项时可删除该标题,标题序号按实际情况编排)

  (1)杜钢军,卢琳琳,杨义明,林海红,张亚平,孙婷,刘伟杰. 过山蕨总黄酮在制备预防和治疗肿瘤药物方面的应用,2014.7.16, 中国, ZL201210486.9

  (2)杜钢军,杨义明,卢琳琳,林海红,刘伟杰,刘迎辉,王莹莹. 皂角刺总黄酮在制备预防和治疗肿瘤药物方面的应用,2014.8.13, 中国, ZL201210486363.1

  (3)杜钢军,卢琳琳,时小燕,黄秀曼,孙婷,张亚平,林海红,卢丹丹,卢建立. 过山蕨的应用以及一种肝功修正茶, 2013.10.23,中国,ZL201110348226.7

  获得学术奖励(仅不列此项时可删除该标题,标题序号按实际情况编排)

  (1) 杜钢军(1/10),肿瘤微环境促进肺癌发生的机制与药物治疗,2016年河南省教育厅科技成果奖一等奖,2016.5.20(杜钢军,李红,林海红,李佳桓,耿胜男,孟明静,杜振华,刘霖鑫,马小方,郭珍珍)